Studies on Arterial Active and Inactive Renins in Spontaneously Hypertensive Rat
نویسندگان
چکیده
منابع مشابه
Arterial hypertrophy in the fetal and neonatal spontaneously hypertensive rat.
Large artery dimensions in prenatal and postnatal normotensive Wistar-Kyoto rats (WKY) and spontaneously hypertensive rats (SHR) were evaluated to determine whether increased medial thickness is evident during early development. Microscopic cross-sections from perfusion-fixed aortas and carotid arteries of fetal (22-day gestation) and neonatal (5-day-old) animals were examined for numbers of la...
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Changes in size, morphology, and certain relevant biochemical components of hearts from spontaneously hypertensive and normal Wistar rats were studied comparatively. Groups of rats were killed at stages which represented developing and stable cardiac hypertrophy and approaching cardiac failure. Mitochondrial content was determined by comparing cytochrome oxidase activity per milligram of heart ...
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The possible role of endothelium in the vascular responses to vasodilator drugs was studied in relation to experimental hypertension. Short ring segments of the thoracic aorta and femoral artery were removed from spontaneously hypertensive rats (SHR) and normotensive WistarKyoto (WKY) rats. They were rubbed on the intimal surface to destruct endothelial cells or unrubbed, and bathed in Krebs-bi...
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Transplantation of arteries into the anterior eye chamber of rats for 8 weeks was used to test the hypothesis that the neurohumoral environment is important in establishing the altered membrane potential (observable during electrogenic ion transport inhibition) of vascular muscle in hypertension. When caudal arteries from 12- to 16-week-old spontaneously hypertensive rats (SHR) or genetically m...
متن کاملStudies on adrenocortical hormone, electrolytes and ultrastructural features of the adrenal cortex in spontaneously hypertensive rat.
Recently, some morphological evidences of hyperfunction of the adrenal cortex have become apparent in spontaneously hypertensive rat (SHR). The present study gave higher fluorimetric assay for either corticosterone and cortisol in SHR at the advanced stage of development of hyperten-sion. Electron microscopically, the mitochondria was closely proliferated, and the smooth surfaced endoplasmic re...
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ژورنال
عنوان ژورنال: Japanese Heart Journal
سال: 1984
ISSN: 0021-4868,1348-673X
DOI: 10.1536/ihj.25.874